Projects
Finocchiaro G.
Dendritic cell immunotherapy of glioblastoma multiforme.
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- Pellegatta S, Poliani PL, Corno D, Menghi F, Ghielmetti F, Suarez-Merino B, Caldera V, Nava S, Ravanini M, Facchetti F, Bruzzone MG, Finocchiaro G.
Neurospheres Enriched in Cancer Stem-Like Cells Are Highly Effective in Eliciting a Dendritic Cell-Mediated Immune Response against Malignant Gliomas.
Cancer Res. 2006 Nov 1;66(21):10247-52.
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- Gabriele Cantini, Federica Pisati, Alfonso Mastropietro, Véronique Frattini, Yoichiro Iwakura, Gaetano Finocchiaro, Serena Pellegatta
A critical role for regulatory T cells in driving cytokines profiles of Th17 cells and their modulation of glioma microenvironment.
Cancer Immunol. Immunother. 2011 Jul DOI 10.1007/s00262-011-1069-4.
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Giangaspero F.
Molecular stratification of high-grade gliomas in children.
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- Buttarelli FR, Massimino M, Antonelli M, Lauriola L, Nozza P, Donofrio V, Arcella A, Oliva MA, Di Rocco C, Giangaspero F.
Evaluation status and prognostic significance of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation in pediatric high grade gliomas.
Childs Nerv Syst. 2010 Aug;26(8):1051-6. Epub 2010 Jun 16.
- Antonelli M, Buttarelli FR, Arcella A, Nobusawa S, Donofrio V, Oghaki H, Giangaspero F.
Prognostic significance of histological grading, p53 status, YKL-40 expression, and IDH1 mutations in pediatric high-grade gliomas.
J Neurooncol. 2010 Sep;99(2):209-15. Epub 2010 Feb 21.
- Manila Antonelli, Maura Massimino, Isabella Morra, Maria Luisa Garrè, Marina Paola Gardiman, Francesca Romana Buttarelli, Antonietta Arcella, Felice Giangaspero
Epression of pERK and pAKT in pediatric high grade astrocytomas: Correlation with YKL40 and prognostic significance.
Neuropathology 2011 Aug doi:10.1111/j.1440-1789.2011.01252.x.
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Salsano E.
Generation of immortalized cell lines of human medulloblastoma through the expression of a dominant negative form of TP53 gene.
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- Ettore Salsano, Rosina Paterra, Miriam Figus, Francesca Menghi, Emanuela Maderna, Bianca Pollo, Carlo Lazzaro Solero, Luca Massimi, Gaetano Finocchiaro
Expression Profile of frizzled receptors in human medulloblastomas
J Neurooncol 2011 Aug DOI 10.1007/s11060-011-0682-6.
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Sardi I., la Marca G., Giovannini M.G., Malvagia S., Guerrini R., Genitori L., Massimino M., Aricò M.
Morphine treatment permits doxorubicin hydrochloride to cross blood brain barrier in rat model.
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- Research project on pediatric brain tumors:
"Alteration of the blood-brain barrier (BBB) using drugs that interact with the P-glycoprotein.
New perspectives for the treatment of "poor-responder" brain tumors of the pediatric age".
Progress Report June 2011.
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- Assessment of the cytotoxic effects of the chemotherapeutic drugs used in the treatment of high-risk brain tumors of the pediatric age.
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